Clinical outcome of using decade-old demineralized dentin matrix in bone grafting: a case report

This case report presents the clinical outcome of using a decade-old autogenous demineralized dentin matrix (DDM) as a bone graft material during immediate implant placement following the extraction of the maxillary right second molar in a 63-year-old female patient. The high collagen density in dentin suggests that tooth-derived bone graft materials may retain their functionality even after long-term storage. In this study, DDM that had been stored for 10 years and re-sterilized using ethylene oxide (EO) gas was grafted to the bone defect around the implant, leading to successful bone regeneration. The radiographic and clinical evaluations over a one-year follow-up period indicated stable bone formation and regeneration, demonstrating the efficacy and safety of long-term stored autogenous DDM. This paper suggests that preparing autogenous tooth-derived bone graft materials in advance can offer practical benefits, even when bone grafting is not immediately required. Moreover, it highlights the potential for long-term stored DDM to be used effectively in dental implant and bone grafting procedures.