Coronavirus disease 2019 (COVID-19) pneumonia presents with severe hypoxemic respiratory failure, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The primary mode of transmission appears to be droplet-borne. Respiratory support and high levels of oxygen are required in the acute treatment of these patients. High-flow therapies have been included as part of the possible management of COVID-19.1,2 One such modality is high-flow therapy, including high-velocity nasal insufflation (HVNI), high-flow nasal oxygen (HFNO), and high-flow nasal cannulation (HFNC).
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Leonard et al. (2020) studied this question.
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