Key result
The risk of hypertension increased with increasing longitude, reaching an adjusted OR of 2.81 (95% CI 1.12-7.08) for longitudes ≥130°E compared to <80°E (Ptrend <0.001).
Why the study?
Is there a spatial variation in hypertension prevalence and an association with altitude, longitude, and latitude in the Chinese population?
Population
451,755 adults aged ≥18 years from a nationally representative sample across 262 county-level regions in 31…
Comparison
Exposure to varying altitude, longitude, and… vs Different geographic exposures
Design
Cross-sectional
Authors
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May inform targeted HTN screening in eastern China; leaves open causal mechanisms needing longitudinal confirmation.
Cross-Sectional (n=451,755)
Yes
Is there a spatial variation in hypertension prevalence and an association with altitude, longitude, and latitude in the Chinese population?
Odds Ratio: 2.81 (95% CI 1.12–7.08)
p-value: p=<0.001
There are remarkably high hypertension prevalence zones in China extending from the southeast to northern and northeastern regions, with risk significantly increasing at higher longitudes.
Pei et al. (2020) conducted a cross-sectional in Hypertension (n=451,755). Increasing longitude vs. Longitude <80°E was evaluated on Risk of hypertension (aOR 2.81, 95% CI 1.12-7.08, p=<0.001). The risk of hypertension increased with increasing longitude, reaching an adjusted OR of 2.81 (95% CI 1.12-7.08) for longitudes ≥130°E compared to <80°E (Ptrend <0.001).
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