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The treatment of all solid tumors, including malignant pleural mesothelioma (MPM), is dependent on (1) macroscopic complete resection and (2) treatment of micrometastatic disease. The role of surgery in the treatment of MPM has been the subject of debate after the recent publication of the Mesothelioma and Radical Surgery (MARS) I trial.1 The International Mesothelioma Interest Group (IMIG) met from September 11 through 14, 2012, in Boston, Mass. During this meeting, more than 500 participants representing all the involved specialty groups met in multiple comprehensive sessions to review, critique, and extend the state of knowledge regarding the role of surgery, including both extended pleurectomy/decortication (P/D) and extrapleural pneumonectomy (EPP), in the treatment of MPM.
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Rusch et al. (2013) studied this question.
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