Why the study?
Existing evidence and guidelines do not comprehensively cover all aspects of left atrial appendage closure including device use, imaging, complications, and management.
This expert consensus statement provides standardized recommendations for the clinical application of left atrial appendage closure in patients with non-valvular atrial fibrillation in China.
Informs LAAO decisions for AF stroke prevention in China; extends international guidance with region-specific graded recommendations.
左心耳封堵（laac）预防非瓣膜性心房颤动卒中的疗效和安全性已被多个随机对照和注册研究所证实，也已被多个指南推荐用于具有高卒中风险房颤患者卒中的预防。然而，laac作为一种新兴技术，其应用不能仅限于指南所涉及适应证和禁忌证的讨论，还应包括该技术所涉及的多种器械和操作的综合应用，影像学指导和评估，并发症处理，围术期及术后用药，以及术后管理等多方面内容。鉴于现有循证医学证据和指南推荐很难涵盖上述所有方面，因此中华医学会心血管病分会和中华心血管病杂志编辑委员会组织不同领域的专家，经充分讨论，最终形成了本共识。根据现有的循证医学证据和临床实践经验，本共识对laac及其相关技术应用的合理性、是否有更多临床获益或更少操作相关并发症给予适合（合理，有更多获益或更少并发症）、不确定（有一定合理性，但尚需更多证据）和不适合（不一定合理，不太可能获益或有更多并发症）3种不同等级的推荐，以指导和规范laac及其相关技术的临床应用。.
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A 2019 study conducted a review in Non-valvular atrial fibrillation. Left atrial appendage closure (LAAC) was evaluated. The Chinese Society of Cardiology expert consensus provides graded recommendations on the comprehensive application of left atrial appendage closure for stroke prevention in atrial fibrillation.
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