Enhanced Na/Li countert r a n s p o rt (NLCT) and Na/H exchange (NHE) been suggested to predict diabetic (1–3). Nevert h e l e s s , studies have excluded this hypothesis(4). We found NHE activity incre a s e d type 1 diabetes (5), yet we could not any relationship between NHE andν r i n a ry albumin excretion rate (UAER) in essential hypertension (6) or in 1 diabetes. There f o re, we measure d≠ ry t h rocyte NHE activity and UAER in nondiabetic family members of 1 diabetic patients with or without nephro p a t h y
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Matteucci et al. (2000) studied this question.