Key result
Pulmonary lymphangitic carcinomatosis from gallbladder cancer can mimic diffuse alveolar haemorrhage and should be considered in patients with haemoptysis and diffuse lung opacity of unknown origin.
Case Report (n=1)
Pulmonary lymphangitic carcinomatosis should be considered in the differential diagnosis for patients presenting with haemoptysis and diffuse lung opacity of unknown origin.
Consider pulmonary lymphangitic carcinomatosis in unexplained haemoptysis with diffuse opacities; extends the differential for gallbladder cancer but remains hypothesis-generating.
Diagnosis in cases with pulmonary lymphangitic carcinomatosis as a primary manifestation is difficult due to unawareness of the cancer. An 81-year-old man was admitted due to a one-week history of dyspnoea and haemoptysis. Chest computed tomography showed diffuse bilateral ground-grass opacity and partial consolidation. We suspected diffuse alveolar haemorrhage. High-dose methylprednisolone and cyclophosphamide did not improve his condition and he died from respiratory failure. Autopsy revealed pulmonary lymphangitic carcinomatosis of whole lungs and primary gallbladder cancer. We should consider pulmonary lymphangitic carcinomatosis in the differential diagnosis of patients with haemoptysis and diffuse lung opacity of unknown origin.
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Higo et al. (2020) conducted a case report in Pulmonary lymphangitic carcinomatosis (n=1). Pulmonary lymphangitic carcinomatosis was evaluated. Pulmonary lymphangitic carcinomatosis from gallbladder cancer can mimic diffuse alveolar haemorrhage and should be considered in patients with haemoptysis and diffuse lung opacity of unknown origin.
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