Key result
Aortofemoral bypass surgery linked to a ~69% return-to-work rate.
Observational (n=51)
Yes
Levamisole administration is associated with reversible thrombocytopenia upon challenge and rechallenge.
May warrant platelet monitoring with levamisole; single case leaves open incidence and generalizability.
31 x 109/1.Levamisole was immediately discontinued and a week later the platelet count had returned to normal (150 x 109/1).Levamisole was restarted in a dose of 100 mg/day.On 21 March 1977 the platelet count had again fallen to 87 x 109/1.The haemoglobin concentration was 13-3 g/dl and the total white cell count 57 x 109/1.Levamisole was discontinued and on 14 April 1977 the platelet count was again normal (159 x 109!1).
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Waters et al. (1977) conducted an observational in Severe intermittent claudication or rest pain (n=51). Aortofemoral bypass surgery was evaluated on Return to work. Aortofemoral bypass surgery enabled 35 of 51 patients (69%) to return to work, including 16 of 29 patients who had been totally lost to productive employment prior to the operation.
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