Key result
Left atrial appendage occlusion in a real-world UK cohort demonstrated a 95% immediate success rate and a 3.5% incidence of major adverse events, with no difference between devices.
Why the study?
Further research is needed to determine whether LAAO should be limited to patients with absolute contraindications to OAT or extended to high bleeding risk patients on VKA and NOACs.
Does Left atrial appendage occlusion (LAAO) demonstrate safety and efficacy in a real-world UK cohort?
Cohort
Does Left atrial appendage occlusion (LAAO) demonstrate safety and efficacy in a real-world UK cohort?
LAAO demonstrates a strong safety profile and high immediate success in a real-world UK cohort, with a significant learning curve effect and comparable outcomes between Watchman and Amplatzer devices.
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Meucci et al. (2017) conducted a cohort in Atrial fibrillation. Left atrial appendage occlusion (LAAO) was evaluated on Major adverse events. Left atrial appendage occlusion in a real-world UK cohort demonstrated a 95% immediate success rate and a 3.5% incidence of major adverse events, with no difference between devices.
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