Key result
Endovascular catheter biopsy yields definitive pulmonary artery sarcoma diagnosis in ~60% of suspected cases.
Why the study?
The diagnosis of pulmonary artery sarcoma is challenging and mainly confirmed using surgical or autopsy specimens.
Does endovascular catheter biopsy establish a definitive diagnosis in patients with suspected pulmonary artery sarcoma?
Case Report (n=5)
No
Does endovascular catheter biopsy establish a definitive diagnosis in patients with suspected pulmonary artery sarcoma?
Endovascular catheter biopsy is a helpful and feasible diagnostic tool for establishing a definitive diagnosis in patients with suspected pulmonary artery sarcoma.
May aid diagnosis in select suspected cases; hypothesis-generating and requires prospective validation before practice change.
The diagnosis of pulmonary artery sarcoma (PAS) is challenging, and its definitive diagnosis is mainly confirmed using specimens obtained during surgery or autopsy. Endovascular catheter biopsy was performed in five patients with suspected PAS to establish a definitive diagnosis. Aspiration biopsy was performed in all patients, and forceps biopsy was performed in one patient. Three patients were diagnosed with PAS, and no definitive diagnosis was obtained in two patients with squamous cell lung carcinoma with pulmonary artery infiltration. Endovascular catheter biopsy is helpful in the diagnosis of PAS and should be performed when a tumor is suspected.
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Fujii et al. (2019) conducted a case report in Suspected pulmonary artery sarcoma (n=5). Endovascular catheter biopsy was evaluated on Definitive histopathological diagnosis.
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