Key result
Surgical resection yields ~10 months disease-free survival in pulmonary artery intimal sarcoma before fatal recurrence.
Why the study?
Pulmonary artery intimal sarcoma is a rare disease that is difficult to diagnose early and often misdiagnosed as pulmonary embolism.
Does surgery, radiotherapy, and chemotherapy improve survival in a patient with pulmonary artery intimal sarcoma?
Case Report (n=1)
No
Does surgery, radiotherapy, and chemotherapy improve survival in a patient with pulmonary artery intimal sarcoma?
Pulmonary artery intimal sarcoma is a rare, aggressive disease often misdiagnosed as pulmonary embolism, where multimodal therapy may offer limited survival benefit.
Surgery may yield transient control in pulmonary artery intimal sarcoma; leaves open whether multimodal therapy meaningfully extends survival in this rare malignancy.
INTRODUCTION: Pulmonary artery intimal sarcoma is a rare disease with no characteristic symptoms. It is difficult to diagnose early and is frequently misdiagnosed as a pulmonary embolism. CASE PRESENTATION: Here we report a case of pulmonary artery intimal sarcoma in a 54-year-old woman presenting with complaints of shortness of breath on exertion. Echocardiography and a computed tomography scan showed that the right pulmonary artery trunk was blocked by a low-density mass. The patient was diagnosed with pulmonary artery intimal sarcoma by pathology and a complete mass resection was performed. After experiencing 10 months of disease-free survival, she was re-admitted because of the recurrence and metastasis of the tumor. Radiotherapy and chemotherapy were performed; however, only limited success was achieved. The patient died 15 months after the initial onset of symptoms. CONCLUSION: Some patients with intimal sarcoma of the pulmonary artery can benefit from radiotherapy and chemotherapy as well as surgery.
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Hong-qing et al. (2008) conducted a case report in Pulmonary artery intimal sarcoma (n=1). Surgery, radiotherapy, and chemotherapy was evaluated on Survival time. A 54-year-old woman with pulmonary artery intimal sarcoma achieved a 10-month disease-free survival after surgery, but died 15 months after symptom onset despite subsequent chemoradiotherapy.
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