High tumor mutational burden (TMB) and PD-L1 have similar predictive utility in 2L+ NSCLC patients (pts) treated with anti-PD-L1 and anti-CTLA-4

This is the authors' abstract. We don't add key points for this paper.

Background: PD-L1 can predict benefit from anti-PD-1/L1 therapies; TMB is an emerging biomarker that may have additional predictive utility. We compared the utility of high TMB and PD-L1 to predict outcomes in NSCLC non-squamous pts treated with anti-PD-L1 (durvalumab) and anti-CTLA-4 monoclonal antibodies (tremelimumab, D+T).