A cationic rhodium(I)/(R)-Segphos® [(4,4′-bi-1,3-benzodioxole)-5,5′-diylbis(diphenylphosphine)] complex catalyzes the highly enantioselective [4 + 2] annulation of 2-alkynylbenzaldehydes with acyl phosphonates, leading to benzopyranones with a phosphonate-substituted quaternary carbon center in moderate to high yields with excellent ee’s.
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Tanaka et al. (2008) studied this question.
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