Key result
Male sex, pleural ADA >88 U/L, and WBC >9.52 x 10^9/L were significant risk factors for tuberculous empyema in pleural tuberculosis patients, while pulmonary TB was protective.
Cohort (n=474)
No
Odds Ratio: 5.763 (95% CI 2.473–13.431)
p-value: p=<0.001
Male sex, high pleural ADA, and high WBC count are significant risk factors for tuberculous empyema in patients with pleural tuberculosis, whereas concurrent pulmonary TB is protective.
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May aid risk stratification in pleural TB; hypothesis-generating and requires prospective validation before clinical use.
Peng et al. (2019) conducted a cohort in Pleural tuberculosis (n=474). White blood cell count >9.52 x 10^9/L vs. White blood cell count ≤9.52 x 10^9/L was evaluated on Tuberculous empyema (OR 5.763, 95% CI 2.473-13.431, p=<0.001). Male sex, pleural ADA >88 U/L, and WBC >9.52 x 10^9/L were significant risk factors for tuberculous empyema in pleural tuberculosis patients, while pulmonary TB was protective.
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