Synthesis and characterization of chroman‐containing compounds and their preliminary assessment of cytotoxicity toward two human cancer cell lines

A series of chroman derivatives were synthesized by employing o‐methyl phenol as a precursor. These compounds were fully characterized using IR, NMR spectroscopic techniques, and elemental analysis. Mechanisms for the formation of the chroman moiety of these compounds were also proposed. MTT (3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide) assay was used to estimate their cytotoxicity toward two cancer cell lines: human ovarian cancer (A2780) and human cervical cancer (Hela).