Key result
Pediatric obesity linked to ~34% higher remnant lipoprotein cholesterol vs low BMI.
Why the study?
The relationship between obesity and remnant lipoproteins and the factors related to remnant lipoprotein in children and adolescents were not well characterized.
Cross-Sectional (n=135)
In children and adolescents, remnant lipoprotein cholesterol is significantly higher in obesity and is independently associated with triglycerides, insulin resistance, and systolic blood pressure.
Obese youth exhibit higher remnant lipoprotein cholesterol tied to metabolic factors; leaves open independent prognostic value for later cardiovascular events.
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Choi et al. (2006) conducted a cross-sectional in Obesity (n=135). Obesity (BMI ≥ 85th percentile) vs. Normal/low weight (BMI < 50th percentile) was evaluated on Remnant lipoprotein cholesterol (RLP-C) level (p=0.027). Obese children and adolescents had significantly higher remnant lipoprotein cholesterol levels compared to those in the low BMI group (7.8 vs 5.8 mg/dL, p=0.027), which independently correlated with triglycerides, insulin resistance, and systolic blood pressure.
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