Although generally viewed as only synergistic with the thyroid hormones, corticosterone (CORT) has many independent effects on anuran larval development. CORT enhances thyroid hormone-induced tail resorption and is involved in immune system, skin gland and gut differentiation. Interactions between the hypothalamo-pituitary-thyroid axis and the corticoid axis regulate hormone secretion, and CORT may be involved in 'stress-induced' metamorphosis.
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Tyrone B. Hayes (1994) studied this question.
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