Comparison of Enhanced Depth Imaging and Swept Source Optical Coherence Tomography in Assessment of Choroidal Thickness in Vogt–Koyanagi–Harada Disease

PURPOSE: To compare enhanced depth imaging (EDI-OCT) and swept source optical coherence tomography (SS-OCT) in assessment of Vogt-Koyanagi-Harada (VKH) disease. METHODS: All consecutive VKH patients seen at Singapore National Eye Centre during 2012-2013 were imaged using both modalities. Subfoveal choroidal thickness (SFCT) was measured by one masked trained observer. RESULTS: A total of 137 pairs of scans were obtained from 48 patients. SFCT was more likely to be measurable on SS-OCT than EDI-OCT (112, 81.8%; 84, 61.3%; p<0.001 Fisher's Exact test). There was good inter-OCT correlation of SFCT when both scans were measureable (mean of the difference in SFCT ± 2 standard deviations (SD) of -14.5 ± 21.0 μm). CONCLUSIONS: SS-OCT images are superior to EDI-OCT but the SFCT measurements are comparable when both are readable.