Key result
A one-stage surgical procedure successfully treated a 38-year-old woman with complex intracardiac leiomyomatosis, resulting in ongoing recovery and no recurrence of cardiac symptoms at 5 months.
Why the study?
Intracardiac leiomyomatosis is a rare condition with complex diagnosis and significant clinical challenges when the tumor invades cardiac structures.
Case Report (n=1)
No
Multimodality imaging including echocardiography, CT, and MRI is essential for the accurate diagnosis and evaluation of intracardiac leiomyomatosis.
Illustrates diagnostic utility of multimodality imaging in intracardiac leiomyomatosis; leaves open need for systematic evaluation.
BACKGROUND: Intracardiac leiomyomatosis (ICL) is an uncommon condition characterized by the proliferation of intravascular tissue within the veins, leading to the development of tumor emboli. This can pose a significant threat to life when the tumor invades cardiac structures. The diagnostic process for this condition is complex and presents considerable challenges. CASE PRESENTATION: We report a case of a 38-year-old female patient whose pulmonary artery computed tomography (CT) revealed low density structure in the branches of the pulmonary artery. Echocardiography revealed a mobile tumor within the right heart chambers and pulmonary trunks as well as characteristic thickening of the ventricular septum consistent with hypertrophic cardiomyopathy (HCM). Magnetic resonance imaging (MRI) revealed a mass in the right anterior uterine wall, extending to the inferior vena cava (IVC) and right iliac vein. Post-surgery histopathological analysis confirmed a diagnosis of intravenous leiomyomatosis (IVL). CONCLUSIONS: When IVL affects the heart, echocardiography is the best diagnostic tool for detecting the disease. CT and MRI are essential in identifying the location and extent of the tumor, as well as in evaluating prognosis.
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Li et al. (2025) conducted a case report in Intracardiac leiomyomatosis (n=1). One-stage surgical resection (total hysterectomy, bilateral oophorectomy, and excision of intracardiac lesions) was evaluated on Surgical outcome and symptom resolution. A one-stage surgical procedure successfully treated a 38-year-old woman with complex intracardiac leiomyomatosis, resulting in ongoing recovery and no recurrence of cardiac symptoms at 5 months.
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