Key result
rtPA successfully resolves left atrial thrombus in an extremely low birth weight infant.
Why the study?
Left atrium thrombus is an extremely rare and potentially life-threatening complication in early infancy, with limited data on its occurrence in extremely low birth weight infants with late-onset circulatory dysfunction.
Case Report (n=1)
Answers are grounded in this paper and cite their sources.
Late-onset circulatory dysfunction in extremely low birth weight infants may be a risk factor for left atrial thrombus, which can be successfully treated with recombinant tissue plasminogen activator.
A left atrium thrombus, potentially a life-threatening complication, is an extremely rare in early infancy. Most cases are caused by mal-placement of central venous catheters or related to congenital heart diseases with left atrial blood congestion. Here we present an extremely low birth weight infant who developed a left atrial thrombus during the course of late onset circulatory dysfunction. The thrombus was successfully treated by recombinant tissue plasminogen activator. A hemodynamically unstable condition like late onset circulatory dysfunction should be taken into consideration as a potential risk condition of this rare disease.
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Ina et al. (2012) conducted a case report in Left atrium thrombus (n=1). Recombinant tissue plasminogen activator was evaluated on Treatment success. Recombinant tissue plasminogen activator successfully treated a left atrial thrombus in an extremely low birth weight infant with late-onset circulatory dysfunction.
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