Lipids participate in many biological processes and take part in a complex network of bioactive compounds and biochemical reactions. They act as inducers, suppressors, modulators, cellular structuring and signaling compounds, and mediators in many pathways, including inflammatory pathways [1,2]. Profiling lipids in human samples might advance the discovery of diagnostic, prognostic, and monitoring disease biomarkers, in addition to allowing the exploration of biological mechanisms [3]. Despite their utility, the variety of lipid species and the different ways to profile them has resulted in a lack of consensus targets that, ultimately, retarded the translation of findings into clinical practices.
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Sanches et al. (2021) studied this question.
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