Key result
Non-invasive atrial fibrosis imaging shows poor reproducibility and weak correlation with histology.
Why the study?
Non-invasive evaluation of atrial fibrosis is limited by difficulties correlating fibrosis imaging with histology and poor reproducibility between observers.
Non-invasive evaluation of atrial fibrosis faces significant limitations, including poor reproducibility and difficulty correlating imaging with histology.
Limits clinical reliance on current atrial fibrosis imaging; leaves open need for reproducible methods with histological validation.
visualization of myocardial fibrotic tissue. The non-invasive evaluation of atrial fibrosis is associated with the risk of recurrence of atrial fibrillation and with electro-anatomical endocardial mapping. We discuss the limitations of these techniques, derived from the difficulty of demonstrating the correlation between fibrosis imaging and histology, and poor intra- and inter-observer reproducibility. The sources of discordance are described, mainly due to image acquisition and processing, and the challenges ahead in an attempt to eliminate differences between operators.
No takes yet. Share an insight, caveat, or question.
Lacalzada-Almeida et al. (2017) conducted a review in Atrial fibrosis. Non-invasive evaluation of atrial fibrosis was evaluated. Non-invasive evaluation of atrial fibrosis faces limitations due to poor intra- and inter-observer reproducibility and difficulty correlating imaging with histology.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: