Synthesis of a series of novel 1,3-diphenyl-4-aryl spiropyrazolines [5.3′] 4′-chromanones has been accomplished in good yields by regioselective 1,3-dipolar cycloaddition of diphenylnitrilimine to 3-arylidene-4-chromanones. X-ray crystal structure analysis of one of the products 4a confirms the structure and the regiochemistry of cycloaddition.
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Raghunathan et al. (1998) studied this question.
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