A single protective group is sufficient at β-mannoside for the selective introduction of both side chains of A. The key glycosylations at the branching point proceed with high regioselectivity when 4,6-O-benzylidene acetal is used as a temporary protecting group. Protected heptasaccharide A was synthesized as a precursor of the undecasaccharide-asparagine found on glycoproteins and shown below.
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Carlo Unverzagt (1994) studied this question.
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