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The synthesis of [14C]Zolpidem, a new hypnotic agent having a non‐benzodiazepine structure, is described. This compound was synthesised in a 64% overall radio‐chemical yield from potassium[14C]cyanide and with a specific radioactivity of 56 mCi/mmol. It was used for pharmacokinetic and drug metabolism studies.
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Allen et al. (1986) studied this question.
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