BACKGROUND: gene encodes protein methylenetetrahydrofolate reductase (MTHFR), an enzyme important in folate metabolism. AIM: gene of healthy subjects from the population. MATERIAL AND METHODS: single nucleotide polymorphisms (SNPs) were analyzed by Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Linkage disequilibrium (LD) between pair of SNPs was calculated through Haploview analysis. RESULTS: ' values of 0.87. CONCLUSION: mutation suggesting decreased viability of embryos with increased numbers of mutant alleles.
No takes yet. Share an insight, caveat, or question.
Nefić et al. (2018) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: