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June 1, 2002Journal of Clinical MicrobiologyOpen Access

High Variability between Results of Different In-House Tests for Cytomegalovirus (CMV) Monitoring and a Standardized Quantitative Plasma CMV PCR Assay

Lutz von Müller Walter Hampl Joachim Hinz Helga Meisel Angela Reip Elisabeth Engelmann Regine Heilbronn Barbara C. Gärtner Oliver H. Krämer Hermann Einsele Holger Hebart Tatjana Ljubicic Jürgen Löffler Thomas Mertens

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Abstract

A total of 2,718 blood samples were analyzed in five virological laboratories for the presence of cytomegalovirus (CMV) by in-house tests and one standardized plasma PCR assay. Results from in-house tests showed remarkable variability. Detection of CMV pp65 antigen or DNA from cells was more sensitive than that by plasma CMV PCR assay.

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Müller et al. (2002) studied this question.

synapsesocial.com/papers/6ab873671f4b23d934885e84 https://doi.org/10.1128/jcm.40.6.2285-2287.2002

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