Key result
In pigs with postweaning multisystemic wasting syndrome, porcine reproductive and respiratory syndrome virus was the most common coinfection (51.9%), with PCV-2 alone found in only 1.9% of cases.
Observational (n=484)
No
In field cases of postweaning multisystemic wasting syndrome, PCV-2 is rarely found alone (1.9%) and is most frequently associated with coinfections such as porcine reproductive and respiratory syndrome virus (51.9%).
High coinfection rates in PMWS cases support targeted diagnostics; leaves open causal roles of PRRSV and co-pathogens.
The prevalence of different pathogens detected in combination with porcine circovirus type 2 (PCV-2) was studied retrospectively in field cases of postweaning multisystemic wasting syndrome (PMWS) diagnosed at the Iowa State University Veterinary Diagnostic Laboratory, Ames, Iowa, between January 2000, and September 2001. The presence of PCV-2 antigen in lymphoid tissues and/or lung, demonstrated by immunohistochemistry, together with moderate to severe lymphoid depletion and/or granulomatous lymphadenitis, was used as the criteria for the diagnosis of PMWS. A total of 484 cases fulfilled these criteria. Most of the cases (294/369) of PMWS occurred in pigs between the ages of 8 and 18 weeks, with a peak at 10 weeks of age. Porcine reproductive and respiratory syndrome virus was detected in 51.9% of the cases, Mycoplasma hyopneumoniae in 35.5%, bacterial septicemia in 14.0%, bacterial pneumonia in 7.6%, swine influenza virus in 5.4%, and PCV-2 alone in 1.9%. In cases with bacterial septicemia the most frequently isolated pathogen was Streptococcus suis. In cases with bacterial pneumonia, Pasteurella multocida was the most prevalent.
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Pallarés et al. (2002) conducted an observational in Postweaning multisystemic wasting syndrome (PMWS) (n=484). Pathogen coinfections was evaluated on Prevalence of different pathogens detected in combination with PCV-2. In pigs with postweaning multisystemic wasting syndrome, porcine reproductive and respiratory syndrome virus was the most common coinfection (51.9%), with PCV-2 alone found in only 1.9% of cases.
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