Key result
Metabolic syndrome is linked to significantly lower ABI values compared to patients without it.
Why the study?
Metabolic syndrome is associated with increased cardiovascular risk, and ankle–brachial index may serve as an indirect marker of subclinical atherosclerosis in these patients.
Do patients with metabolic syndrome have lower ankle-brachial index values compared to patients without metabolic syndrome?
Case-Control (n=98)
Do patients with metabolic syndrome have lower ankle-brachial index values compared to patients without metabolic syndrome?
Patients with metabolic syndrome have significantly lower ankle-brachial index values, supporting its use as a noninvasive marker for subclinical atherosclerosis and elevated cardiovascular risk in this population.
Supports ABI evaluation for subclinical atherosclerosis in metabolic syndrome; hypothesis-generating and should not yet change practice.
A BSTRACT Background: Metabolic syndrome (MetS) refers to a group of conditions that are associated with increased cardiovascular risk. Ankle–brachial index (ABI) is a noninvasive, inexpensive way of assessing the blood flow in the lower limbs and may be useful as an indirect marker of subclinical atherosclerosis. Aim and Objective: To study and compare ABI values between patients with MetS and patients without MetS. Materials and Methods: A total of 98 patients attending the outpatient department between October 2018 and September 2020 were included in the study. They were categorized as MetS and non-MetS as per the National Cholesterol Education Program Adult Treatment Panel III guidelines. They were tested for ABI with a handheld Doppler. The ABI values were compared between the two groups. Results: Among 98 patients, 49 were cases and 49 as controls. ABI values were found to be 1.09 ± 0.12 among the cases and 1.22 ± 0.05 among the controls and were found to be statistically significant ( P < 0.001). Conclusion: The patients with MetS had lower ABI compared with the patients who did not have MetS. ABI can be used as an indirect marker of atherosclerosis and can be used in routine clinical assessment for identifying patients at a higher cardiovascular risk.
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Jawahar et al. (2022) conducted a case-control in Metabolic syndrome (n=98). Metabolic syndrome vs. Patients without metabolic syndrome was evaluated on Ankle-brachial index (ABI) values (p=< 0.001). Metabolic syndrome was associated with significantly lower ankle-brachial index values compared to patients without metabolic syndrome (1.09 vs 1.22; P<0.001).
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