Key result
Anakinra resolves recurrent HKU1-associated pericarditis in a patient with systemic lupus erythematosus.
Why the study?
The presence of human coronavirus HKU1 infection associated with pericardial inflammation had not been previously reported.
Case Report (n=1)
Answers are grounded in this paper and cite their sources.
This case report highlights a rare association between human coronavirus HKU1 infection and recurrent pericarditis in a patient with SLE, which was successfully managed with anakinra.
The presence of human coronavirus HKU1 infection associated with pericardial inflammation is not reported. We are reporting a young woman with systemic lupus erythematosus, who was positive for HKU1 during her pericarditis flare. Diagnostic imaging demonstrated pericardial effusion, edema, and late gadolinium enhancement on cardiac magnetic resonance imaging and echocardiography. She was on multiple anti-inflammatory medications and achieved remission with anakinra. Her management and a brief literature review is also presented.
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Furqan et al. (2021) conducted a case report in Recurrent pericarditis and systemic lupus erythematosus (n=1). Human coronavirus (HKU1) infection was evaluated on Remission of pericarditis. A young woman with systemic lupus erythematosus and human coronavirus HKU1-associated recurrent pericarditis achieved remission following treatment with anakinra.
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