Evaluation of lesions of uncertain malignant potential (B3) at core needle biopsy using magnetic resonance imaging: A new approach warrants prospective studies

Percutaneous needle biopsy plays a crucial role in deciding the management of suspicious breast findings, both in the clinical and screening setting. The evolution from fine needle aspiration to core needle biopsy was partly to reduce inadequacy rate and to provide histological information. However, an important fraction of core needle biopsies are classified as ‘borderline’ (B3) or ‘lesions of uncertain malignant potential’, a category that includes several types of histological lesions.1 Due to the uncertain and variable frequency of malignancy at final (excisional) pathology, women with B3 lesions are usually managed with surgery, and the possibility of close follow-up or alternate management for particular histological subgroups is debated.