The bacteriochlorophyll-d producing strain of bacterial Chlorobium forma thiosulfatophilum(NCIB Strain 8327) alters its chromophore by modification of its 4- ane 5-substituents using methylations with S-adenosylmethionine; with time, the strain produces bacteriochlorophyll-c by performing macrocyclic rather than side chain methylation.
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Smith et al. (1987) studied this question.