Familial screening in Wilson’s disease: Think at the previous generation!

Wilson’s disease (WD) is an autosomal recessive disease caused by mutations in the ATP7B gene, resulting in accumulation of copper in various organs including liver, cornea, and brain [1]. AADSL and EASL Guidelines have been published to help physicians in diagnosis and treatment [2,3]. We report diagnosis of WD in a 43-year-old asymptomatic father after his daughter had presented with a typical hepatic WD, and want to focus on recommendations about familial screening.