Key result
Emergency resection plus chemotherapy yields disease-free survival at 6 months in primary cardiac lymphoma.
Why the study?
Primary cardiac lymphomas are extremely rare with no consensus on treatment strategy and often diagnosed only postoperatively, affecting treatment and outcomes.
Case Report (n=1)
Emergency resection followed by postoperative chemotherapy resulted in a disease-free status at six months for a young patient with primary cardiac lymphoma.
Hypothesis-generating for emergency resection plus chemotherapy in primary cardiac lymphoma; does not support practice change without further evidence.
Primary lymphomas of the heart are extremely rare, accounting for 2% of all primary cardiac tumors. Due to the rare presentation, there is no proper consensus available on treatment strategy. Preoperative confirmation of the pathology is fundamental in guiding an early treatment plan, which allows for improved prognosis. Unfortunately, in most cases, primary cardiac lymphoma is only identified on postoperative histopathological analyses, which affect the treatment plan and outcome. Here, we report a unique case of primary cardiac lymphoma presented with dyspnea and reduced effort tolerance. Young age, rapid onset of symptom, and absence of cardiac risk factors prompted us towards further imaging and emergency resection. The patient received a course of postoperative chemotherapy and was disease-free on six months of follow-up.
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Aimanan et al. (2016) conducted a case report in Primary cardiac lymphoma (n=1). Emergency resection and postoperative chemotherapy was evaluated on Clinical outcome at follow-up. Emergency resection followed by postoperative chemotherapy for primary cardiac lymphoma resulted in the patient being disease-free at six months of follow-up.
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