A new treatment is suggested to prevent root resorption of heterotransplanted teeth. After conservative root canal treatment, the root surface was treated with concentrated citric acid solution to demineralize the root surface. The demineralized collagenous matrix was then treated with n‐acetylcysteine to inhibit collagenase activity and collagen degradation. Two cases are presented. The initial results supported the notion that anti‐collagenase drugs might be useful in preventing resorption of mineralized collagenous matrices such as cementum, dentin and bone.
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Sperling et al. (1986) studied this question.
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