All articles of this category Trifluoromethylated amides are prepared in a simple one-flask reaction via the Ritter reaction of the corresponding trifluoromethylated silyl ethers, which themselves are readily obtained from the starting ketones and trifluoromethyltrimethylsilane. The yields are good to average. Ritter reaction - (trifluoromethyl)trimethylsilane - trifluoromethylated tertiary amides - hydrolysis - acetonitrile
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Tongco et al. (1997) studied this question.