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Labeling diabetes: Streptozotocin-derived, cyanine-5.5-labeled imaging probes were synthesized and tested with the beta-cell-mimic INS-1E cell line in cell uptake assays, as well as by flow cytometry and confocal microscopy. Both probes showed superb labeling of INS-1E cells and human pancreatic islets (see graph) with no toxicity.
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Ran et al. (2007) studied this question.
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