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January 6, 2015EntropyOpen Access

Assessment of Time and Frequency Domain Entropies to Detect Sleep Apnoea in Heart Rate Variability Recordings from Men and Women

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Key result

Sex-specific HRV entropy analysis detects sleep apnoea with ~85% accuracy in women.

  • n=188

Why the study?

Entropy measures of heart rate variability have shown utility to characterize heart dynamics, but their ability to detect sleep apnoea-hypopnea syndrome and gender differences was not fully assessed.

Does spectral entropy and multiscale entropy analysis of heart rate variability accurately detect sleep apnoea-hypopnea syndrome, and does performance differ by gender?

Population

188 subjects evaluated for sleep apnoea-hypopnea syndrome

Comparison

Spectral entropy and multiscale entropy analyses of HRV recordings

Design

Cross-sectional study

Authors

GGGonzalo C. Gutiérrez‐TobalDÁDaniel ÁlvarezJGJavier Gómez‐Pilar

Discussion

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Overview

Gender-stratified HRV entropy models may aid SAHS detection; leaves open prospective validation before clinical use.

Study Design

Type

Cross-Sectional (n=188)

Structured PICO

Does spectral entropy and multiscale entropy analysis of heart rate variability accurately detect sleep apnoea-hypopnea syndrome, and does performance differ by gender?

P
Population
188 subjects evaluated for sleep apnoea-hypopnea syndrome using heart rate variability recordings to assess gender-specific diagnostic models.
E
Exposure
Spectral entropy (SE) and multiscale entropy (MsE) analysis of heart rate variability (HRV) recordings
O
Outcome
Detection of sleep apnoea-hypopnea syndrome (SAHS) measured by accuracy and area under the ROC curve (AROC)surrogate

Heart rate variability entropy measures can accurately detect sleep apnea, with diagnostic performance significantly improved when models are separated by gender.

Cite This Study

Gutiérrez‐Tobal et al. (2015) conducted a cross-sectional in Sleep apnoea-hypopnea syndrome (SAHS) (n=188). Spectral entropy (SE) and multiscale entropy (MsE) analysis of HRV was evaluated on Diagnostic accuracy and area under the ROC curve (AROC) for SAHS. Spectral and multiscale entropy analysis of heart rate variability detected sleep apnoea with higher accuracy when modeled separately by gender, achieving 85.2% accuracy (AROC 0.951) in women.

synapsesocial.com/papers/6ab8a9f34a7eedc8ee330282https://doi.org/10.3390/e17010123
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Predicting sleep apnoea syndrome from heart period: a time-frequency wavelet analysis2003 · 108 citations
  2. 2Application of a Modified Entropy Computational Method in Assessing the Complexity of Pulse Wave Velocity Signals in Healthy and Diabetic Subjects2014 · 31 citations
  3. 3Photoplethysmography pulse rate variability as a surrogate measurement of heart rate variability during non-stationary conditions2010 · 465 citations
  4. 4Sample entropy of the main atrial wave predicts spontaneous termination of paroxysmal atrial fibrillation2009 · 61 citations
  5. 5Is the Normal Heartbeat Chaotic or Homeostatic?1991 · 286 citations