Ammodaucus leucotrichus L. (Apiaceae) is a rarely investigated important medicinal plant endemic to North African countries. The essential oil of A. leucotrichus L. seeds obtained by hydro-distillation and SPME extraction methods were analyzed by Gas Chromatography-Mass Spectrometry (GC-MS) technique. Twenty two components were identified in the hydro-distilled oil amounting to 97.04 % of the total oil content. The oil was dominated by oxygenated monoteprenes (87.32 %) represented by perilla aldehyde (84.43 %). A total of thirty four components accounting for 99.88 % of the total composition were characterized in the SPME oil. Monoterpene hydrocarbons had the highest contribution to the SPME oil (87.40 %) with terpinolene being the main component of the fraction (69.21%). The hydro-distilled oil was screened for its antimicrobial activity and was found to be inactive against Escherichia coli, Pseudomonas aeruginosa and Salmonella typhi. The pure oil was most active against Micrococcus luteus while moderately active against Klebsiella pneumonia, Staphylococcus aureus and Bacillus subtilis. Moreover, the essential oil showed no activity against MCF7 and T47D cancer cell lines. The investigation revealed qualitative and quantitative differences between the hydro-distilled and SPME oils of the Algerian A. leucotrichus L. seeds.
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Zarga et al. (2013) studied this question.
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