Key result
Negative appendectomy was associated with higher 30-day mortality (SMR 8.95; 95% CI 6.68-12.61) compared to perforated appendicitis, and mortality remained increased for up to 5 years.
Why the study?
Does the diagnosis and surgical method of appendectomy influence short- and long-term mortality in patients undergoing appendectomy?
Population
223,543 appendectomy patients treated from 1987 to 2006 in Sweden
Comparison
Appendectomy vs Expected mortality and comparisons between…
Design
Cohort
Follow-up
up to 5 years
Authors
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May prompt refined diagnostic protocols to avoid unnecessary appendectomies; leaves open causal pathways and need for prospective validation.
Cohort (n=223,543)
Yes
Does the diagnosis and surgical method of appendectomy influence short- and long-term mortality in patients undergoing appendectomy?
Effect estimate: SMR 8.95 (95% CI 6.68-12.61)
Negative appendectomy is associated with excess short- and long-term mortality, highlighting the need for improved preoperative diagnosis to avoid unnecessary surgery.
Roland Erik Andersson (2012) conducted a cohort in Suspected appendicitis (n=223,543). Negative appendectomy vs. Perforated appendicitis was evaluated on 30-day mortality (SMR 8.95, 95% CI 6.68-12.61). Negative appendectomy was associated with higher 30-day mortality (SMR 8.95; 95% CI 6.68-12.61) compared to perforated appendicitis, and mortality remained increased for up to 5 years.
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