This review summarizes our research into the synthesis and structure-activity relationships of epolactaene, neoechinulin A, plakevulin A, pseudodeflectusin and ustusorane C. These natural products are attractive in view of their apoptosis-inducing activity, cytoprotective activity against peroxynitrite, inhibitory activity against DNA polymerases, and cytotoxicity in cancer cells.
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Kouji Kuramochi (2013) studied this question.
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