Key result
Propensity score matching can overcome the main limitations of conventional observational studies and could serve as an alternative to RCTs for evaluating contrast-induced acute kidney injury.
Why the study?
Can propensity score matching serve as an alternative to randomized controlled trials for evaluating acute kidney injury after contrast media administration?
Systematic Review
Can propensity score matching serve as an alternative to randomized controlled trials for evaluating acute kidney injury after contrast media administration?
Propensity score matching may serve as a viable methodological alternative to randomized controlled trials for evaluating the risk of contrast-induced acute kidney injury.
PSM strengthens causal inference on contrast-AKI risk in observational data; leaves open need for RCTs before changing practice.
OBJECTIVE: Controversy exists regarding the causal relationship between contrast media administration and the development of acute kidney injury because prospective randomized controlled trials (RCTs) confirming this relationship are lacking. In this systematic review we address studies using propensity score matching with regard to contrast-induced acute kidney injury and possible implications for future practice guideline development. CONCLUSION: Propensity score matching can overcome the main limitations of conventional observational studies and could serve as an alternative in the absence of RCTs.
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Dekkers et al. (2018) conducted a systematic review in Acute kidney injury after contrast media administration. Contrast media administration was evaluated on Contrast-induced acute kidney injury. Propensity score matching can overcome the main limitations of conventional observational studies and could serve as an alternative to RCTs for evaluating contrast-induced acute kidney injury.
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