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December 1, 2003The Journal of Immunology

Paradoxical Dampening of Anti-Islet Self-Reactivity but Promotion of Diabetes by OX40 Ligand

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Authors

NMNatalia Martín‐OrozcoProvidence Health CareZCZhibin ChenUniversity of MiamiLPLaurent PoirotTxcell (France)

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Martín‐Orozco et al. (2003) studied this question.

synapsesocial.com/papers/6ab8bc3e9660f9d384ca59aehttps://doi.org/10.4049/jimmunol.171.12.6954
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Acceleration of spontaneous diabetes in TCR-beta-transgenic nonobese diabetic mice by beta-cell cytotoxic CD8+ T cells expressing identical endogenous TCR-alpha chains1996 · 129 citations
  2. 2Intracellular Signaling of gp34, the OX40 Ligand: Induction of c- jun and c- fos mRNA Expression Through gp34 upon Binding of Its Receptor, OX401999 · 46 citations
  3. 3The OX40 Costimulatory Receptor Determines the Development of CD4 Memory by Regulating Primary Clonal Expansion2000 · 418 citations
  4. 4Regulation of Diabetes Development by Regulatory T Cells in Pancreatic Islet Antigen-Specific TCR Transgenic Nonobese Diabetic Mice2002 · 68 citations
  5. 5Ox40 Costimulation Enhances the Development of T Cell Responses Induced by Dendritic Cells In Vivo2002 · 91 citations