Key result
Non-obese women with PCOS were significantly more likely to have a family history of PCOS, irregular menses, hirsutism, acne, and recurrent miscarriages than obese women with PCOS.
Cross-Sectional (n=300)
Non-obese women with PCOS may have a stronger genetic predisposition and more pronounced clinical symptoms of hyperandrogenism and reproductive dysfunction compared to obese women with PCOS.
Introduction: Obesity becomes a recent worldwide epidemic and it is close associated with PCOS.Currently there are not enough researches which can let to understand the interplay between PCOS and its features including anovulation and infertility and androgen status and obesity.The aim of the study was to identify relations between PCOS and obesity.Methodology: Cross-sectional study was conducted for the period 2014-2016 and included 300 of patients with PCOS.The following categorical variables were studied: age, marital status, weight, BMI, family history, frequency of irregular periods, subfertility, hirsutism, acne, skin hyperpigmentation.The analyses were performed using the SPSS package version 17.0 (SPSS Inc., Chicago, IL, USA). Results and conclusion:Current research showed that non-obese women with PCOS more often had family history of PCOS and were significantly more likely to have such symptoms as irregular menses, hirsutism, acne vulgaris and recurrent miscarriages than women with obesity and PCOS.However there is a need for more researches regarding to risk factors, etiology and pathogenesis of PCOS in order to identify the underlying causes.
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A 2017 study conducted a cross-sectional in Polycystic Ovarian Syndrome (PCOS) (n=300). Obesity vs. Non-obese was evaluated on Relations between PCOS and obesity (symptoms and family history). Non-obese women with PCOS were significantly more likely to have a family history of PCOS, irregular menses, hirsutism, acne, and recurrent miscarriages than obese women with PCOS.
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