January 1, 1984Journal of the Chemical Society Chemical Communications

The addition of chlorosulphonyl isocyanate to an allenyl acetate. The preparation of a versatile intermediate for antibiotic synthesis

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Abstract

Chlorosulphonyl isocyanate and 1-acetoxy-3-methylbuta-1,2-diene react to form 4-acetoxy-3-(1-methylethylidene)azetidinone, a useful presursor to the skeletons of several antibiotics.

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Cite This Study

Buynak et al. (1984) studied this question.

synapsesocial.com/papers/6ab8cfcb005eb9ed582b3c53 https://doi.org/10.1039/c39840000948

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Abstract

Chlorosulphonyl isocyanate and 1-acetoxy-3-methylbuta-1,2-diene react to form 4-acetoxy-3-(1-methylethylidene)azetidinone, a useful presursor to the skeletons of several antibiotics.