Key result
Unexplained CCU chest pain reveals esophageal dysfunction in ~62% of patients at 3 years.
Why the study?
The causes and prognosis of chest pain of unknown origin in non-infarction coronary care unit patients were not well characterized.
Population
55 consecutive CCU patients with chest pain of unknown origin at hospital discharge
Comparison
Signs of oesophageal dysfunction vs signs of ischaemic heart disease
Design
Cohort study
Authors
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May warrant oesophageal evaluation in unexplained CCU chest pain; leaves open diagnostic impact and requires prospective validation.
Cohort (n=55)
In CCU patients discharged with chest pain of unknown origin, ischaemic heart disease is the most common cause and carries the worst prognosis, though oesophageal dysfunction is highly prevalent and should be considered in the differential diagnosis.
Areskog et al. (1981) conducted a cohort in Chest pain of unknown origin (n=55). Chest pain of unknown origin was evaluated on Signs of oesophageal dysfunction (OD) and ischaemic heart disease (IHD) at 3-year follow-up. Among CCU patients with chest pain of unknown origin, signs of oesophageal dysfunction were found in 62% and ischaemic heart disease in 28% at 3-year follow-up.
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