Neurological Disorders Complicating Pregnancy and its Obstetric Outcomes

The study included all pregnant women with preexisting neurologic disorders or newly diagnosed neurologic disorders during pregnancy.Pregnant women with eclampsia were excluded from the study.The detailed history of the patients, clinical examination findings, and basic investigations were studied.The management by various multidisciplinary teams as per institutional guidelines was noted.Radiological imaging was done in relevant patients as per the advice of the neurophysicians or neurosurgeons.The outcome measures studied included maternal and neonatal factors such as parity index, booking status, gestational age at the time of delivery, mode of delivery, birth weight of the newborn, fetal anomalies, Appearance, Pulse, Grimace, Activity, and Respiration (APGAR) score at 5 minutes, distribution of neurological diseases during pregnancy, neurological manifestations, and associated medical and obstetric complications. Statistical AnalysisData were analyzed using the Statistical Package for the Social Sciences version 16 after it was manually entered in Microsoft Excel.Interquartile ranges were deduced for variables such as gestational IntroductIonNeurological disorders are very rarely encountered in pregnancy.It can be either a preexisting condition before pregnancy or develop during pregnancy.It is a challenge to diagnose and differentiate a few new onset neurological disorders during pregnancy from pregnancy complications manifesting with neurologic features like eclampsia.It is associated with increased morbidity and mortality.It is an important indirect cause of maternal death in India and around the globe.1,2 Due to its rarity in its occurrence in pregnancy, a high degree of suspiciousness and involvement of the concerned team is needed for the diagnosis and management of the patient.The altered physiology during pregnancy imposes a challenge to diagnose the various disorders.The duration of pregnancy and concern regarding the fetus make it tricky to choose appropriate investigation and treatment.Hence, this study was carried out with the intention of determining the most common neurological disorders during pregnancy and their distribution, clinical presentation, and obstetric outcome in our institution. objectIveThe objective of our study is to find the common neurological disorders complicating pregnancy and their obstetric outcome. MaterIals a n d MethodsThis was a 3-year retrospective study done at St John's Medical College, SJNAHS, Bengaluru, Karnataka, India, from January 2016 to December 2018.We included all the pregnant women with neurologic disorders admitted to the Obstetrics and Gynecology Department of our hospital.Demographic data, details of the respective neurologic disorders, and obstetric outcomes of the patients were noted.