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February 1, 1989Proceedings of the National Academy of SciencesOpen Access

Bacteriophage T4 DNA topoisomerase is the target of antitumor agent 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA) in T4-infected Escherichia coli.

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Authors

AHA C HuffUniversity of North Carolina at Chapel HillJLJ K LeatherwoodKKKenneth N. KreuzerDuke Medical Center

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Huff et al. (1989) studied this question.

synapsesocial.com/papers/6ab8dd9596da824e5b875168https://doi.org/10.1073/pnas.86.4.1307
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The problems of eukaryotic and prokaryotic DNA packaging and in vivo conformation posed by superhelix density heterogeneity1977 · 233 citations
  2. 2DNA Modification and Cancer1981 · 690 citations
  3. 3Characterization of a camptothecin-resistant human DNA topoisomerase I.1988 · 82 citations