Key result
The Medical Decompression protocol significantly reduced the time to progress diet compared to standard care in late-stage cancer patients with functional intestinal obstruction (1.39 vs 3.46 days, p<0.01).
Observational (n=104)
No
Absolute Event Rate: 1.39% vs 3.46%
p-value: p=<0.01
May support faster diet advancement in palliative obstruction; hypothesis-generating, needs randomized confirmation.
At the end of life, many patients suffer from a syndrome that simulates classic small bowel obstruction. The traditional approach to intestinal obstruction is relief of pressure in the gastrointestinal tract using mechanical methods such as naso-gastric tube insertion and suctioning.
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Calves et al. (2017) conducted an observational in Functional Intestinal Obstruction in late-stage cancer (n=104). Medical Decompression (MD) protocol vs. Standard care (non-medical decompression) was evaluated on Days to progress diet (propensity-matched cohort) (p=<0.01). The Medical Decompression protocol significantly reduced the time to progress diet compared to standard care in late-stage cancer patients with functional intestinal obstruction (1.39 vs 3.46 days, p<0.01).
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