Hydrophosphonylation of Nanoparticle Schiff Bases as a Mean for Preparation of Aminophosphonate-Functionalized Nanoparticles

The development of nanotechnology is responsible for an increase in the achievements in medical diagnostics and in the preparation of new therapeutic vehicles. In particular, magnetic nanoparticles with a modified surface are a very attractive alternative to deliver therapeutic agents. We describe the modification of the surface of the iron oxide nanoparticles with aminophosphonic acids by applying the classic hydrophosphonylation approach.